Structural Bioinformatics: Practical Guide

This site provides a guide to protein structure and function, including various aspects of structural bioinformatics. It covers some basic principles of protein structure like secondary structure elements, domains and folds, databases, relationships between protein amino acid sequence and the three-dimensional structure. In addition, some basics principles of sequence analysis, homology modeling and structure-based drug design are covered. In the related tutorials I use resources freely available on the web. Although, you should know that there are commercial program packages, which include many features not available in the free versions. In the experimental part I have included some basics of protein crystallization and protein crystallography.




Tutorials in sequence alignment and homology modeling

alignment & modeling tutorials

Please note that the site is updated few times each year, which means not continuously! I am sorry for any inconvenience.