Structural Bioinformatics: Practical Guide

This site provides a guide to structural bioinformatics, including some aspects of structure-based drug design and the experimental methods of structural biology. We cover some basics of the principles of protein structure like secondary structure elements, domains and folds, databases. We also discuss relationships between protein amino acid sequence and the three-dimensional structure. In addition, some basics principles of sequence analysis and homology modeling are covered. In the related tutorials I use resources freely available on the web. Although, you should know that there are commercial program packages, which include many features not available in the free resources. In the experimental part I have included some basics of protein crystallization and protein crystallography.

Please note that this site is not a comprehensive textbook on the subject. It is based on a course in structural bioinformatics, which I have been running at the Department of Biochemistry and Structural Biology, Lund University, Sweden. The full course includes lectures, tutorials and practical exercises that together constitute an essential complement to the content of this site.

A note for visitors
Please note that the site is updated few times/year, which means not continuously! I am sorry for any inconvenience. The updates may include some minor design issues, updates of links present at the site, etc. Also please note, I am not able to help you with your projects, I simply don't have enough time, I am sorry.
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