Structural Bioinformatics: Practical Guide

This site provides a guide to protein structure and function, including various aspects of structural bioinformatics. It covers some basic principles of protein structure like secondary structure elements, domains and folds, databases, relationships between protein amino acid sequence and the three-dimensional structure. In addition, some basics principles of sequence analysis, homology modeling and structure-based drug design are covered. In the related tutorials I use resources freely available on the web. Although, you should know that there are commercial program packages, which include many features not available in the free versions. In the experimental part I have included some basics of protein crystallization and protein crystallography.

structure

sequence

experimental

A note for visitors
Please note that the site is updated few times/year, which means not continuously! I am sorry for any inconvenience.
The updates may include some minor design issues, updates of links present at the site, text updates to adjust the site to SEO requirements, or major updates of the teaching content. If you prefer a pdf version of the material presented here please contact me using the
contact form provided.